In a large trifle dish or a glass bowl, layer half of the pound cake cubes at the bottom.
Add half of the sliced strawberries on top of the pound cake layer.
Spoon half of the vanilla pudding over the strawberries, spreading it evenly.
Add half of the whipped cream on top of the pudding layer, smoothing it out gently.
Repeat the layering process with the remaining pound cake, strawberries, pudding, and whipped cream.
Top the final layer of whipped cream with the blueberries, arranging them decoratively.
If desired, sprinkle powdered sugar over the top for added sweetness.
Chill the trifle in the refrigerator for at least 1 hour before serving to allow the flavors to meld.
Garnish with fresh mint leaves just before serving for a pop of color and freshness.